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Conclusion: FOXO4-DRI promotes the nuclear export of phosphorylated P53 by inhibiting the binding of FOXO4 to P53 in endothelial cells, thereby facilitating the apoptosis of senescent endothelial cells and alleviating aging

COVID-19, however, appears to trigger a severe cytokine storm syndrome in pulmonary structures, resulting in oxidative stress, exacerbated inflammation and alveolar injury

2007, pp

Neurotrophins perform their functions by binding to two different types of receptors, tyrosine kinase receptors and neurotrophic receptor 75

Cartilage is constantly rebuilt and we are usually not aware of its existence until it is damaged, which is manifested by difficulties and aches when moving and by swellings

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